The MYOT Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to LGMD1, and Myotilin. This antibody recognizes Human antigen. The MYOT Antibody (Center) has been validated for the following applications: ELISA, and Western Blot.
Description
This gene encodes a cystoskeletal protein which plays a
significant role in the stability of thin filaments during muscle
contraction. This protein binds F-actin, crosslinks actin
filaments, and prevents latrunculin A-induced filament disassembly.
Mutations in this gene have been associated with limb-girdle
muscular dystrophy and myofibrillar myopathies. Several
alternatively spliced transcript variants of this gene have been
described, but the full-length nature of some of these variants has
not been determined